Embryonic Schwann cell development: the biology of Schwann cell precursors and early Schwann cells
نویسندگان
چکیده
منابع مشابه
Schwann cell development in embryonic mouse nerves.
Previously we proposed that Schwann cell development from the neural crest is a two-step process that involves the generation of one main intermediate cell type, the Schwann cell precursor. Until now Schwann cell precursors have only been identified in the rat, and much remains to be learned about these cells and how they generate Schwann cells. Here we identify this cell in the mouse and analy...
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OF THE DISSERTATION ........................................................................... ii ACKNOWLEDGEMENTS ................................................................................................ v TABLE OF CONTENTS .................................................................................................. vii LIST OF FIGURES AND TABLES......................................
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Immature Schwann cells found in perinatal rodent nerves are generated from Schwann cell precursors (SCPs) that originate from the neural crest. Immature Schwann cells generate the myelinating and non-myelinating Schwann cells of adult nerves. When axons degenerate following injury, Schwann cells demyelinate, proliferate and dedifferentiate to assume a molecular phenotype similar to that of imma...
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Background: Adipose-derived stem cells (ADSCs) are a population of pluripotent cells used for tissue engineering purposes. The main purpose of the present study was to transdifferentiate the ADSCs to Schwann-like cells and to determine the intensity of apoptosis in ADSCs during the transdifferentiation process. Methods: ADSCs were isolated from the inguinal adipose tissue of adult rats and the ...
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The CNS contains relatively few unmyelinated nerve fibers, and thus benefits from the advantages that are conferred by myelination, including faster conduction velocities, lower energy consumption for impulse transmission, and greater stability of point-to-point connectivity. In the PNS many fibers or regions of fibers the Schwann do not form myelin. Examples include C fibers nociceptors, postg...
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ژورنال
عنوان ژورنال: Journal of Anatomy
سال: 1997
ISSN: 0021-8782,1469-7580
DOI: 10.1046/j.1469-7580.1997.19140501.x